USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: PSME3_HUMAN USC-OGP 2-DE database:  PSME3_HUMAN PSME3_HUMAN General information about the entry View entry in simple text format Entry name PSME3_HUMAN Primary accession number P61289 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma;. Gene name Name=PSME3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1247: pI=5.77; Mw=31502 Cross-references UniProtKB/Swiss-Prot P61289; PSME3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PSME3_HUMAN Primary accession number P61289 Secondary accession number(s) A8K9A3 O35563 P97373 Q12920 Q13172 Q9BQD9 Sequence was last modified on  May 10, 2004 (version 1) Annotations were last modified on  March 15, 2017 (version 142) Name and origin of the protein Description RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma; Gene name Name=PSME3 Encoded on Name=PSME3 Keywords Acetylation; Alternative splicing; Apoptosis; Cell cycle; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Proteasome; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U11292; AAB60335.1; -; mRNA EMBL BT019386; AAV38193.1; -; mRNA EMBL AK292618; BAF85307.1; -; mRNA EMBL AK074999; BAG52046.1; -; mRNA EMBL AC016889; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471152; EAW60893.1; -; Genomic_DNA EMBL BC001423; AAH01423.1; -; mRNA EMBL BC002684; AAH02684.1; -; mRNA EMBL BC008020; AAH08020.1; -; mRNA EMBL U25756; AAA93227.1; -; Genomic_DNA CCDS CCDS11442.1; -. [P61289-2]; . CCDS CCDS45689.1; -; . CCDS CCDS59290.1; -. [P61289-3]; . PIR I38702; A60537; . RefSeq NP_005780.2; NM_005789.3. [P61289-1]; . RefSeq NP_789839.1; NM_176863.2. [P61289-2]; . UniGene Hs.152978; -; . ProteinModelPortal P61289; -; . SMR P61289; -; . BioGrid 115492; 172; . IntAct P61289; 84; . MINT MINT-5002653; -; . STRING 9606.ENSP00000293362; -; . iPTMnet P61289; -; . PhosphoSitePlus P61289; -; . SwissPalm P61289; -; . BioMuta PSME3; -; . DMDM 47117724; -; . EPD P61289; -; . PaxDb P61289; -; . PeptideAtlas P61289; -; . PRIDE P61289; -; . DNASU 10197; -; . Ensembl ENST00000293362; ENSP00000293362; ENSG00000131467. [P61289-2]; . Ensembl ENST00000441946; ENSP00000409487; ENSG00000131467. [P61289-3]; . Ensembl ENST00000590720; ENSP00000466794; ENSG00000131467. [P61289-1]; . GeneID 10197; -; . KEGG hsa:10197; -; . UCSC uc002ibq.5; human; . CTD 10197; -; . DisGeNET 10197; -; . GeneCards PSME3; -; . HGNC HGNC:9570; PSME3; . HPA CAB008388; -; . HPA HPA012510; -; . MIM 605129; gene; . neXtProt NX_P61289; -; . OpenTargets ENSG00000131467; -; . PharmGKB PA33916; -; . eggNOG KOG4470; Eukaryota; . eggNOG ENOG410XQVX; LUCA; . GeneTree ENSGT00510000046374; -; . HOVERGEN HBG053745; -; . InParanoid P61289; -; . KO K06698; -; . OMA PCNKPLC; -; . OrthoDB EOG091G0GX7; -; . PhylomeDB P61289; -; . TreeFam TF106236; -; . Reactome R-HSA-1169091; Activation of NF-kappaB in B cells; . Reactome R-HSA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; . Reactome R-HSA-1236974; ER-Phagosome pathway; . Reactome R-HSA-1236978; Cross-presentation of soluble exogenous antigens (endosomes); . Reactome R-HSA-174084; Autodegradation of Cdh1 by Cdh1:APC/C; . Reactome R-HSA-174113; SCF-beta-TrCP mediated degradation of Emi1; . Reactome R-HSA-174154; APC/C:Cdc20 mediated degradation of Securin; . Reactome R-HSA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; . Reactome R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; . Reactome R-HSA-180534; Vpu mediated degradation of CD4; . Reactome R-HSA-180585; Vif-mediated degradation of APOBEC3G; . Reactome R-HSA-187577; SCF(Skp2)-mediated degradation of p27/p21; . Reactome R-HSA-195253; Degradation of beta-catenin by the destruction complex; . Reactome R-HSA-202424; Downstream TCR signaling; . Reactome R-HSA-211733; Regulation of activated PAK-2p34 by proteasome mediated degradation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2871837; FCERI mediated NF-kB activation; . Reactome R-HSA-349425; Autodegradation of the E3 ubiquitin ligase COP1; . Reactome R-HSA-350562; Regulation of ornithine decarboxylase (ODC); . Reactome R-HSA-382556; ABC-family proteins mediated transport; . Reactome R-HSA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA; . Reactome R-HSA-4608870; Asymmetric localization of PCP proteins; . Reactome R-HSA-4641257; Degradation of AXIN; . Reactome R-HSA-4641258; Degradation of DVL; . Reactome R-HSA-5358346; Hedgehog ligand biogenesis; . Reactome R-HSA-5362768; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; . Reactome R-HSA-5607761; Dectin-1 mediated noncanonical NF-kB signaling; . Reactome R-HSA-5607764; CLEC7A (Dectin-1) signaling; . Reactome R-HSA-5610780; Degradation of GLI1 by the proteasome; . Reactome R-HSA-5610783; Degradation of GLI2 by the proteasome; . Reactome R-HSA-5610785; GLI3 is processed to GLI3R by the proteasome; . Reactome R-HSA-5632684; Hedgehog 'on' state; . Reactome R-HSA-5658442; Regulation of RAS by GAPs; . Reactome R-HSA-5668541; TNFR2 non-canonical NF-kB pathway; . Reactome R-HSA-5676590; NIK-->noncanonical NF-kB signaling; . Reactome R-HSA-5678895; Defective CFTR causes cystic fibrosis; . Reactome R-HSA-5687128; MAPK6/MAPK4 signaling; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-68827; CDT1 association with the CDC6:ORC:origin complex; . Reactome R-HSA-68949; Orc1 removal from chromatin; . Reactome R-HSA-69017; CDK-mediated phosphorylation and removal of Cdc6; . Reactome R-HSA-69229; Ubiquitin-dependent degradation of Cyclin D1; . Reactome R-HSA-69481; G2/M Checkpoints; . Reactome R-HSA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; . Reactome R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; . ChiTaRS PSME3; human; . GeneWiki PSME3; -; . GenomeRNAi 10197; -; . PMAP-CutDB P61289; -; . PRO PR:P61289; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000131467; -; . CleanEx HS_PSME3; -; . ExpressionAtlas P61289; baseline and differential; . Genevisible P61289; HS; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0008537; C:proteasome activator complex; IEA:InterPro; . GO GO:0000502; C:proteasome complex; TAS:ProtInc; . GO GO:0061133; F:endopeptidase activator activity; IDA:UniProtKB; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0097371; F:MDM2/MDM4 family protein binding; IDA:UniProtKB; . GO GO:0002039; F:p53 binding; IDA:UniProtKB; . GO GO:0031145; P:anaphase-promoting complex-dependent catabolic process; TAS:Reactome; . GO GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; TAS:Reactome GO GO:0006915; P:apoptotic process; IEA:UniProtKB-KW; . GO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB; . GO GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0038061; P:NIK/NF-kappaB signaling; TAS:Reactome; . GO GO:0090263; P:positive regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; TAS:Reactome; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0000209; P:protein polyubiquitination; TAS:Reactome; . GO GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; . GO GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IBA:GO_Central; . GO GO:0043488; P:regulation of mRNA stability; TAS:Reactome; . GO GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB; . GO GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome; . GO GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0002223; P:stimulatory C-type lectin receptor signaling pathway; TAS:Reactome; . GO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome; . GO GO:0055085; P:transmembrane transport; TAS:Reactome; . GO GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:Reactome; . GO GO:0060071; P:Wnt signaling pathway; planar cell polarity pathway; TAS:Reactome Gene3D 1.20.120.180; -; 1; . Gene3D 1.20.5.120; -; 1; . InterPro IPR009077; Proteasome_activ_pa28; . InterPro IPR003186; Proteasome_activ_pa28_C; . InterPro IPR003185; Proteasome_activ_pa28_N; . PANTHER PTHR10660; PTHR10660; 1; . Pfam PF02251; PA28_alpha; 1; . Pfam PF02252; PA28_beta; 1; . SUPFAM SSF47216; SSF47216; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]